Chinese Journal of Organic Chemistry ›› 2021, Vol. 41 ›› Issue (12): 4704-4711.DOI: 10.6023/cjoc202111037 Previous Articles     Next Articles

ARTICLES

空气氛围下可见光诱导的硫酚氧化脱氢偶联

陈幸, 周璇, 姬小趁, 黄华文*()   

  1. 湘潭大学化学学院 湖南湘潭 411105
  • 收稿日期:2021-11-25 修回日期:2021-12-11 发布日期:2021-12-15
  • 通讯作者: 黄华文
  • 基金资助:
    国家自然科学基金(22071211); 湖南省自然科学基金(2020JJ3032)

Visible Light-Induced Aerobic Oxidative Dehydrogenative Coupling of Thiophenols

Xing Chen, Xuan Zhou, Xiaochen Ji, Huawen Huang()   

  1. College of Chemistry, Xiangtan University, Xiangtan, Hunan 411105
  • Received:2021-11-25 Revised:2021-12-11 Published:2021-12-15
  • Contact: Huawen Huang
  • Supported by:
    National Natural Science Foundation of China(22071211); Natural Science Foundation of Hunan Province(2020JJ3032)

α-Thioetherified carbonyl compounds widely exist in nature and various industries. They are important intermediates for the synthesis of heterocycles. The traditional synthesis methods of carbonyl thioethers usually need the pre- functionalization of substrates to convert them from nucleophiles to electrophiles. The synthesis methods are cumbersome and complex. Therefore, it is very important to explore a new thioetherification reaction of carbonyl compounds. The synthesis of thioether compounds by oxidative dehydrogenation coupling reaction of ketones and thiophenols under visible light was developed. In the photocatalytic system, without any metal, the reaction successfully realizes high atomic economy and wide substrate application range using cheap and easily available air as oxidant, and provides a simpler method for the direct construction of C—S bond.

Key words: photocatalysis, C—S bond construction, dehydrogenation coupling, thioether