The asymmetric synthesis of chiral N-substituted-α- aminophosphonates

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Chin. J. Org. Chem. ›› 1996, Vol. 16 ›› Issue (3): 238-241. Previous Articles Next Articles

Original Articles

N-取代-α-氨基膦酸酯的不对称合成

王敏;吴广利;王志强;万宝杰

北京农业大学应用化学系

发布日期:1996-06-25

The asymmetric synthesis of chiral N-substituted-α- aminophosphonates

WANG MIN;WU ANLI;WANG ZHIQIANG;WAN BAOJIE

Published:1996-06-25

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Abstract

Chiral N-substituted-α-aminophosphonates were synthesized stereoselectively by addition of dialkylphosphites and chiral imines, using (S)-α-iso-propylbenzylamine as chiral inducing agent. The de was up to 72% and yields were 30~90%. The stereoeffects on the optical and chemical yields were discussed briefly.

Key words: PLANT GROWTH REGULATORS, PHOSPHORUS ACID ESTERS, SCHIFF BASE, CHIRALITY, INDUCED REACTION, HERBICIDES, BACTERICIDAL AGENTS

CLC Number:

O627
Q51

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WANG MIN;WU ANLI;WANG ZHIQIANG;WAN BAOJIE. The asymmetric synthesis of chiral N-substituted-α- aminophosphonates[J]. Chin. J. Org. Chem., 1996, 16(3): 238-241.

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N-取代-α-氨基膦酸酯的不对称合成

The asymmetric synthesis of chiral N-substituted-α- aminophosphonates

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