Preparation of pyridylethynyl benzonitriles

Chin. J. Org. Chem. ›› 2001, Vol. 21 ›› Issue (7): 514-517. Previous Articles Next Articles

吡啶乙炔苯甲腈类化合物的制备

汪志勇;李前荣;姜超;周存六;郭庆祥

中国科学技术大学化学系.合肥(230026)

发布日期:2001-07-25

Preparation of pyridylethynyl benzonitriles

Wang Zhiyong;Li Qianrong;Jiang Chao;Zhou Cunliu;Guo Qingxiang

Univ Sci & Technol China, Dept Chem.Hefei(230026)

Published:2001-07-25

Abstract

Heck reaction involves pyridylethynyl or phenylethynyl group were inverstigated in depth. It was found that solvent had a significant effect on the reaction. As a results, the palladium-catalyzed coupling reaction was improved and was used for preparation of pyridylethynyl benzonitrile compounds. four novel pyridylethynyl benzonitrile compounds were synthesized, illnstrating an effective and convenient method for the synthesis of this class of compounds.

Key words: PYRIDINE P, ACETYLENE P, BENZONITRILE P, PALLADIUM, COUPLING REACTION, CATALYTIC REACTION

CLC Number:

O621

Cite this article

Wang Zhiyong;Li Qianrong;Jiang Chao;Zhou Cunliu;Guo Qingxiang. Preparation of pyridylethynyl benzonitriles[J]. Chin. J. Org. Chem., 2001, 21(7): 514-517.

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吡啶乙炔苯甲腈类化合物的制备

Preparation of pyridylethynyl benzonitriles

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