Chin. J. Org. Chem. ›› 2006, Vol. 26 ›› Issue (12): 1623-1630. Previous Articles     Next Articles

Review

2-碘酰基苯甲酸(2-Iodoxybenzoic acid, IBX)在有机合成中的应用

覃开云,苏桂发*,饶万平,谭光明   

  1. (广西师范大学化学化工学院 桂林 541004)
  • 收稿日期:2005-04-19 修回日期:2006-03-10 出版日期:2006-11-21 发布日期:2006-11-21
  • 通讯作者: 苏桂发

Application of 2-Iodoxybenzoic Acid (IBX) in Organic Synthesis

QIN Kai-Yun,SU Gui-Fa*,RAO Wan-Ping,TAN Guang-Ming   

  1. (College of Chemistry and Chemical Engineering, Guangxi Normal University, Guilin 541004)
  • Received:2005-04-19 Revised:2006-03-10 Online:2006-11-21 Published:2006-11-21
  • Contact: SU Gui-Fa

This paper reviews the applications of 2-iodoxybenzoic acid (IBX) in organic synthesis, focusing on the oxidations of IBX with alcohols, nitrogen-containing, sulfur-containing organic compounds, selective oxidation at carbon adjacent to aromatic systems, preparations of α,β-unsaturated carbonyl compounds and lactones, etc. These reactions take place in mild conditions, in high yields, and with high chemoselecticity. IBX-amide, IBX-ester and polymer-supported IBX analogues, which are mild, non-explosive, highly soluble, and/or recyclable, are also discussed.

Key words: organic synthesis, application, 2-iodoxybenzoic acid (IBX)