Chin. J. Org. Chem. ›› 2009, Vol. 29 ›› Issue (11): 1836-1839. Previous Articles     Next Articles

Reviews

三甲基溴代硅烷促进的非环状与环状缩醛(酮)的合成

武利强* 杨春广 杨利敏 杨丽娟   

  1. (新乡医学院药学院 新乡 453003)
  • 收稿日期:2008-10-16 修回日期:2009-04-11 发布日期:2009-06-18
  • 通讯作者: 武利强 E-mail:wliq1974@sohu.com

Trimethylsilylbromide-Promoted Synthesis of Acyclic and Cyclic Acetals

Wu, Liqiang*    Yang, Chunguang       Yang, Limin       Yang, Lijuan   

  1. (School of Pharmacy, Xinxiang Medical College, Xinxiang 453003)
  • Received:2008-10-16 Revised:2009-04-11 Published:2009-06-18

Trimethylsilylbromide-promoted synthesis of acyclic and cyclic acetals was realized in high yields from carbonyl compounds by reaction with alcohol, diol at room temperature in the presence of trimethyl orthoformate or triethyl orthoformate. All products were characterized by 1H NMR spectrum and elemental analysis.

Key words: trimethylsilylbromide, acyclic and cyclic acetal, synthesis