Chin. J. Org. Chem. ›› 1990, Vol. 10 ›› Issue (4): 350-352. Previous Articles     Next Articles

Original Articles

Z-和E-细辛醚的合成

王植材;蒋腊生;许杏祥   

  1. 中山大学化学系;中国科学院上海有机化学研究所
  • 发布日期:1990-08-25

Synthesis of Z- and E- asarone

WANG ZHICAI;JIANG LASHENG;XU XINGXIANG   

  • Published:1990-08-25

Stereoselective synthesis of asarone (I) by the reaction of 2,4,5-trimethoxybenzaldehyde and the appropriate Grignard or Wittig reagent under different conditions was described. In the approach with Grignard reaction, the major product was a-(E)-asarone, while the major product was either a-(E)- or b-(Z)-asarone in the Wittig approach depending on the reaction conditions.

Key words: METHOXY GROUP, WITTIG REACTION, ORGANIC SYNTHESIS, GRIGNARD REACTION, BENZALDEHYDE, STEREOSELECTIVITY, ASARONE

CLC Number: