Chin. J. Org. Chem. ›› 2010, Vol. 30 ›› Issue (06): 797-808. Previous Articles     Next Articles

Reviews

5-取代嘧啶核苷类似物的设计、合成及生物活性研究进展

张新迎,王洋洋,冯东,范学森   

  1. 河南师范大学化学与环境科学学院 新乡 453007
  • 收稿日期:2009-07-31 修回日期:2009-10-09 出版日期:2010-06-25 发布日期:2009-11-17
  • 通讯作者: 范学森 E-mail:xuesen.fan@yahoo.com
  • 基金资助:

    国家级.国家自然科学基金

Progress in the Design, Synthesis and Biological Studies of Novel 5-Substituted Pyrimidine Nucleoside Mimics

ZHANG Xin-Ying, WANG Yang-Yang, FENG Dong, FAN Xue-Sen   

  1. School of Chemistry and Environmental Sciences, Henan Normal University, Xinxiang 453007
  • Received:2009-07-31 Revised:2009-10-09 Online:2010-06-25 Published:2009-11-17

The recent development on the design, synthesis and biological studies of novel 5-substituted pyrimidine nucleosides as potential antiviral, anti-tumor, antibacterial and antileishmanial agents is reviewed.

Key words: 5-substituted pyrimidine nucleoside, synthesis, biological activity