Chin. J. Org. Chem. ›› 2015, Vol. 35 ›› Issue (2): 259-272.DOI: 10.6023/cjoc201409026 Previous Articles     Next Articles

Reviews

手性烯烃配体在不对称催化领域的最新进展

冯向青, 杜海峰   

  1. 中国科学院化学研究所 北京分子科学国家实验室 分子识别与功能院重点实验室 北京 100190
  • 收稿日期:2014-09-11 修回日期:2014-10-16 出版日期:2015-02-25 发布日期:2014-10-22
  • 通讯作者: 杜海峰 E-mail:haifengdu@iccas.ac.cn
  • 基金资助:

    国家自然科学基金(No. 21222207)资助项目.

Application of Chiral Olefin Ligands in Asymmetric Catalysis

Feng Xiangqing, Du Haifeng   

  1. Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190
  • Received:2014-09-11 Revised:2014-10-16 Online:2015-02-25 Published:2014-10-22
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21222207).

As a novel class of potential ligands, chiral olefin ligands have attracted much attention. Chiral olefin ligands exhibit higher activity and selectivity than the traditional nitrogen, phosphine, oxide ligands in some reactions, and solved some problems that other ligands could not do. To enhance the coordination of the olefin ligands and the metal, heteroatoms were introduced to its backbone, several hybrid olefin ligands have been developed to increase the diversity of the ligands for further expanding the application of chiral olefin ligands. In this review, the recent advances in the development of chiral diene ligands, chiral phosphine olefin ligands and chiral sulfur olefin ligands, and their application in transition-metal catalyzed asymmetric reactions are reviewed.

Key words: chiral olefin ligand, asymmetric catalysis, chiral diene ligand, chiral P/alkene ligand, chiral S/alkene ligand