Chinese Journal of Organic Chemistry ›› 2021, Vol. 41 ›› Issue (7): 2610-2620.DOI: 10.6023/cjoc202103020 Previous Articles     Next Articles



邹晓亮a,b, 徐森苗a,*()   

  1. a 中国科学院兰州化学物理研究所 羰基合成与选择氧化国家重点实验室 兰州 730000
    b 中国科学院大学 北京 100049
  • 收稿日期:2021-03-10 修回日期:2021-03-17 发布日期:2021-03-25
  • 通讯作者: 徐森苗
  • 基金资助:

Recent Progress in Iridium-Catalyzed Remote Regioselective C—H Borylation of (Hetero)Arenes

Xiaoliang Zoua,b, Senmiao Xua()   

  1. a State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000
    b University of Chinese Academy of Sciences, Beijing 100049
  • Received:2021-03-10 Revised:2021-03-17 Published:2021-03-25
  • Contact: Senmiao Xu
  • Supported by:
    National Natural Science Foundation of China(91956116)

(Hetero)Aryl boronic acids and their derivatives have been widely used in synthetic chemistry, material sciences, and drug discovery. Accordingly, the development of novel synthetic methods towards these structures has received a great deal of attention. In particular, Ir-catalyzed C—H borylation represents one of the most efficient methods. Due to the restriction of the reaction mechanism, regioselective controllable C—H borylation of Ir catalysis is a formidable challenge, and it is also an important development direction in this area. In this review, the recent progress in Ir-catalyzed remote selective C—H borylation of arenes is systematically discussed.

Key words: C—H activation, (hetero)aryl boronates, synthetic methods, borylation