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化学学报
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化学学报 ›› 2012, Vol. 70 ›› Issue (10): 1227-1231.DOI: 10.6023/A1112122 上一篇    下一篇

研究论文

氟吗啉合成工艺热危险性及动力学研究

程春生, 秦福涛, 魏振云, 任忠宝, 明旭   

  1. 沈阳化工研究院有限公司 沈阳科创化学品有限公司 沈阳 110144
  • 投稿日期:2011-12-12 修回日期:2012-03-01 发布日期:2012-05-28
  • 通讯作者: 程春生 E-mail:chengchunsheng@sinochem.com

Thermal Hazard and Kinetic Study for Synthesis Process of Flumorph

Cheng Chunsheng, Qin Futao, Wei Zhenyun, Ren Zhongbao, Ming Xu   

  1. Shenyang Research Institute of Chemical Industry Co., LTD., Shenyang Sciencreat Chemicals Co., LTD., Shenyang 110144
  • Received:2011-12-12 Revised:2012-03-01 Published:2012-05-28

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1511

被引次数

11 | 3

氟吗啉是一种新型杀菌剂, 合成工艺热危险性和动力学研究将解决工程问题, 并保障安全生产. 采用差示扫描量热-热重分析仪(DSC-TG)测试主要原料、中间体和产品的热稳定性, 采用反应量热仪(RC1)研究反应热行为, 同时开展反应动力学研究. 研究结果显示, 主要中间体(3,4-二甲氧基苯基)(4-氟苯基)甲酮吸热分解温度为559.3 K, 乙酰吗啉吸热分解温度为478.2 K, 氟吗啉吸热分解温度为638.6 K. 氟吗啉合成反应摩尔放热量为15.44 kJ/mol, 绝热温升ΔTad为9.1 K, 本研究合成工艺的热危险性较小. 氟吗啉合成反应动力学方程为：rA=kcAa=8.34×10-3CA0.57, 对主要中间体(3,4-二甲氧基苯基)(4-氟苯基)甲酮的反应级数为0.57 级.

关键词: 氟吗啉, 差示扫描量热-热重分析仪(DSC-TG), 分解温度, 反应量热(RC1), 热危险性, 动力学

Flumorph is a new fungicide, thermal hazard study and kinetic analysis for the process will solve engineering problems and ensure production safety. The thermostability of main materials is tested by using differential scanning calorimetry-thermogravimetric analyzer (DSC-TG). The reaction thermal behavior is studied by using reaction calorimeter (RC1), and the kinetic study of the reaction is carried out in this paper. The conclusion of this study is that the endothermic decomposition temperature of main intermediate of (3,4-dimethoxyphenyl)(4-fluorophenyl)methanone is 559.3 K. The exothermic decomposition temperature of N-acetylmorpholine is 478.2 K and the endothermic decomposition temperature of flumorph is 638.6 K. The exothermic energy of the reaction for synthesis of flumorph is 15.44 kJ/mol, and the adiabatic temperature rise is 9.1 K. This process is with lower thermal hazard. The reaction kinetic equation is rA=kcAa=8.34×10-3CA0.57, and the reaction order is 0.57 for (3,4-dimethoxyphenyl)(4-fluorophenyl)- methanone.

Key words: flumorph, differential scanning calorimetry-thermogravimetric analyzer (DSC-TG), decomposition temperature, reaction calorimeter (RC1), thermal hazards, kinetics