Acta Chimica Sinica ›› 1983, Vol. 41 ›› Issue (6): 514-518. Previous Articles     Next Articles

Original Articles

固液相烃基化反应的研究 I.以碳酸钾为碱的丙二酸乙二酯和氰乙酸乙酯的烃基化反应

彭祥运;徐成治   

  1. 安徽中医学院药学系;上海第一医学院药学系
  • 发布日期:1983-06-15

Alkylation in solid-liquid two phase systems i. alkylation of diethyl malonate and ethyl cyanoacetate using potassium carbonate as a base

PENG XIANGYUN;XU CHENGZHI   

  • Published:1983-06-15

The alkylation of diethyl malonate and ethyl cyanoacetate using powdered potassium carbonate asa base in the absence of solvent and other catalyst is studied. The features of this method are: simple preparative procedure, reproducible yield and easy control of monoalkylation. The reaction mechanism is discussed briefly.

Key words: REACTION MECHANISM, ETHYL ESTER, ALKYLATION, POTASSIUM CARBONATE, CARBOXYLIC ACID ESTER, MALONIC ACID P, CYANOACETIC ACID P

CLC Number: