A mild selective method for deacetylation has been developed. It' s application to deacetylation of glucosides was studied using catalytic amount of dibutyltin oxide as catalyst and methanol as solvent. The scope and mechanism of the deprotection reaction have been discussed. The present results showed that the method is suitable for deactylation of glycosides. Structures of the products were identified by 'H NMR, IR and elemental analysis. Deacetylation reaction is quite important in organic synthesis. It is the first report to use dibutyltin oxide as catalytic agent in deprotection reaction.

Key words: ORGANO TIN COMPOUNDS, GLYCOSIDE, 1HNMR, IR, ELEMENTAL ANALYSIS, REACTION MECHANISM