Acta Chimica Sinica ›› 2009, Vol. 67 ›› Issue (16): 1843-1850. Previous Articles     Next Articles

Original Articles

稀土、钼酸、糠醛缩水杨酰肼三元配合物的合成、 表征及生物活性的研究

夏庆春a 沈智慧a 何其庄*,a 许东芳a 彭子飞a 邵超英b

  

  1. (a上海师范大学生命与环境科学学院 上海 200234)
    (b东华大学化学化工与生物工程学院 上海 201620)

  • 投稿日期:2008-12-24 修回日期:2009-02-17 发布日期:2009-08-28
  • 通讯作者: 何其庄

Synthesis, Characterization and Biological Activity of Rare Earth Complexes with Fural Salicylhydrazone and Molybdic Acid

Xia, Qingchun a Shen, Zhihui a He, Qizhuang *,a Xu, Dongfang a
Peng, Zifei a Shao, Chaoying b
  

  1. (a Department of Chemistry, Shanghai Normal University, Shanghai 200234)
    (b College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620)
  • Received:2008-12-24 Revised:2009-02-17 Published:2009-08-28

Using a reflux condensation method and a low-temperature solid phase method, eight kinds of new ternary complexes were synthesized with rare earth chloride, molybdenum acid and fural salicylhydrazone. Their compositions were characterized by elemental analysis, molar conductance, FT-IR, UV-vis, TG-DTA, TC-ICP, XRD and XPS, and confirmed to be Re(HL)MoO4Cl•6H2O (HL: fural salicylhydrazone). The antibacterial activity testing shows that all the complexes exhibit antibacterial ability against Escherichia coli and Staphylococcus aureus. The antimicrobial spectrum of the complexes is broad. MTT was used to study the anticancer ability of the complexes, which indicates that the cancer cells were killed by the complexes. All the complexes have potential drug application.

Key words: complex, antibacterial, anti-tumour