A series of molecular template polymers (MTP) were prepared by the molecular template technology in toluene, methanol, chloroform or acetonitrile with coumarin as the template molecule, methacrylic acid (MAA), acrylamide (MA), 2-vinylpyridine (2-VP) or 4-vinylpyridine (4-VP) as the functional monomer, and ethylene glycol dimethacrylate (EGDMA) as a crosslinker, respectively. The effects of the composition of polymerization systems on the adsorption property of MTP were studied. The results indicated that the template polymer prepared using MAA as functional monomer and acetonitrile as porogen with the molar ratio of coumarin∶MAA∶EGDMA＝1∶4∶30 added in the polymerization, exhibited advantageous characteristics of high binding activity, optimal imprinting effect and good selectivity compared with the other MTP prepared in this work, and could be used as adsorption material for separation of coumarin from the traditional Chinese medicine Angelica dahunica.

Key words: coumarin, molecular template polymer, molecular template technique, adsorption