有机化学 ›› 2024, Vol. 44 ›› Issue (11): 3456-3466.DOI: 10.6023/cjoc202404019 上一篇    下一篇

研究论文

钯催化SO2插入的烯丙基酯与芳基碘化物的还原偶联反应

张鑫伟, 林水侦, 黄晓雷*()   

  1. 浙江师范大学化学与材料科学学院 先进催化材料教育部重点实验室 浙江金华 321004
  • 收稿日期:2024-04-13 修回日期:2024-05-13 发布日期:2024-06-07
  • 基金资助:
    国家自然科学基金(22101259); 浙江省自然科学基金(LQ22B020002)

Pd-Catalyzed Reductive Cross-Coupling of Allylic Esters with Aryl Iodides Involving the Insertion of SO2

Xinwei Zhang, Shuizhen Lin, Xiaolei Huang*()   

  1. Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, College of Chemistry and Materials Science, Zhejiang Normal University, Jinhua, Zhejiang 321004
  • Received:2024-04-13 Revised:2024-05-13 Published:2024-06-07
  • Contact: *E-mail:huangxl@zjnu.edu.cn
  • Supported by:
    National Natural Science Foundation of China(22101259); Zhejiang Provincial Natural Science Foundation(LQ22B020002)

报道了一种钯催化二氧化硫插入的烯丙基酯和芳基碘化物的亲电-亲电还原偶联反应. 该反应使用锰粉作为高活性还原剂、廉价易得的焦亚硫酸钠作为气态二氧化硫替代物, 具有反应性好、选择性高以及底物范围广等特点.

关键词: 钯催化, 还原偶联, 烯丙基酯, 焦亚硫酸钠, 二氧化硫

A Pd-catalyzed electrophilic-electrophilic reductive cross-coupling of allylic esters with aryl iodides involving the insertion of SO2 has been reported. This reaction employs manganese powder as reductant, cheap and readily available sodium metabisulfite as SO2 substitute, and features good reactivity, high rselectivity and broad substrate scope.

Key words: palladium-catalysis, reductive cross-coupling, allylic ester, sodium metabisulfite, sulfur dioxide