有机化学 ›› 1988, Vol. 8 ›› Issue (2): 120-125. 上一篇    下一篇

研究论文

烯胺酮与烯胺酯的交叉缩合反应及自缩合反应的区域选择性研究

康国钧;卓金聪;章本礼;高振衡   

  1. 南开大学化学系
  • 发布日期:1988-04-25

Study on the regioselectivity of the self-condensation reactions of enamino-ketones and their cross-condensation reactions with Enamino-esters

KANG GUOJUN;ZHUO JINCONG;ZHANG BENLI;GAO ZHENHENG   

  • Published:1988-04-25

研究了烯胺酮与烯胺酯的交叉缩合反应及自缩合反应.烯胺酮与烯胺酯以(3C+3C)缩合反应形成多取代芳环化合物, 具有区域选择性. 为了进一步研究其反应机理, 我们选用不对称β-二酮与烯胺酯反应, 并用波谱和X-射线衍射技术确定了产物的结构, 讨论了反应机理.

关键词: 缩合反应, 反应机理, 选择性, 羧酸酯, 酮, 烯胺, &beta, -双酮类

The title reactions gave substituted aromatic compounds in a (3 C + 3 C) condensation reaction with regioselectivity. E.g., self-condensation of enamino ketone I in the presence of CF3CO2H gave 23.1% benzoate II. The mechanism of the reactions is discussed.

Key words: CONDENSATION REACTION, REACTION MECHANISM, SELECTIVITY, CARBOXYLIC ACID ESTER, KETONE, ENAMINES, &beta, -DIKETONES

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