有机化学 ›› 1988, Vol. 8 ›› Issue (5): 466-469. 上一篇    下一篇

研究论文

钟琦;邵建国;刘长庆   

  1. 扬州师范学院化学系
  • 发布日期:1988-10-25

Double Michael addition of isopropylidene malonate

ZHONG QI;SHAO JIANGUO;LIU CHANGQING   

  • Published:1988-10-25

报导了丙二酸亚异丙酯与某些亲电双共轭烯酮的双Michael加成, 探讨了影响反应的因素和控制单、双Michael加成的条件.

关键词: 反应机理, 相转移催化, 丙二酸 P, 丙二酸 P, 共轭双键化合物, 加成反应, 异丙酯, 异丙酯, 亲电反应, 烯酮, 迈克尔加成反应

The Michael addition of isopropylidenemalonate to (RCH:CH)2CO (R = Ph, 4-ClC6H4, 4-MeOC6H4, 3-ClC6H4, 2-MeOC6H4) under the phase transfer conditions is reported, and a convenient method of controlling single and double Michael addition is presented. Using this method, five single addition products I and five double addition products II were prepared

Key words: REACTION MECHANISM, PHASE TRANSFER CATALYSIS, MALONIC ACID P, MALONIC ACID P, CONJUGATED DOUBLE BOND COMPOUNDS, ADDITION REACTION, ISOPROPYL ESTER, ISOPROPYL ESTER, ELECTROPHILIC REACTION, KETENE, MICHAEL ADDITION REACTION

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