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有机化学
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有机化学 ›› 1995, Vol. 15 ›› Issue (1): 76-80. 上一篇    下一篇

研究论文

相转移催化合成羧酸醚酯类化合物

唐代华;何兴涛;李菊仁;龚健   

  1. 湖南师范大学化学系
  • 发布日期:1995-02-25

Synthesis of carboxylic ether-ester compounds by PTC

TANG DAIHUA;HE XINGTAO;LU JUREN;GONG JIAN   

  • Published:1995-02-25

被引次数

30

将[N(Bu)~4]Br或FeCl~3-PEG-400作为相转移催化剂,应用于α-氯代烷基烷基醚与无水乙酸钠(或无水甲酸钠)之间的亲核取代反应, 以合成具有RCOOCHR'OR''型结构的羧酸醚酯类香料化合物, 产物产率可提高10%. 中间化合物与产物的结构均经IR, NMR 与元素分析证实.

关键词: 合成, 相转移催化, 羧酸醚酯类

[N(Bu)~4]Br or FeCl~3-PEG-400 was used as a phase-transfer catalyst to the nucleophilic substitution reaction of α-chloroalkyl alkyl ethers with anhydrous sodium acetate (or anhydrous sodium formate), the yield has increased by 10% . The structures of the intermediates and the products were confirmed by IR, NMR and elementary analysis.

Key words: SYNTHESIS, PHASE TRANSFER CATALYSIS

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