有机化学 ›› 1995, Vol. 15 ›› Issue (6): 609-614. 上一篇    下一篇

研究论文

Fura-型新荧光试剂的合成和结构与性能关系的研究

杨LI萍;赵菁菁;张小兵;张熊德;朱培闳   

  1. 华东师范大学化学系;中国科学院上海生理研究所
  • 发布日期:1995-12-25

Synthesis of new Fura-like fluorescent reagents for the determination of cytosolic [Ca^2^+] and studies on the structure- activity relationship

YANG PING;ZHAO JINGJING;ZHANG XIAOBING;ZHANG XIONGDE;ZHU PEIHONG   

  • Published:1995-12-25

本文报道了测定细胞内游离[Ca^2^+]的新荧光试剂Fura-4, Fura-5的合成方法。研究了不同取代基对缩合反应的影响及取代基的结构对荧光性能的影响。

关键词: 缩合反应, 结构与性能关系, 取代基效应, 荧光试剂

This paper reports the synthesis of two new highly fluorescent reagents, Fura-4 and Fura-5 for the determination of Cytosolic free [Ca^2^+]. The substituent effect on the condensa-tion reaction and fluorescent properties were also discussed.

Key words: CONDENSATION REACTION, STRUCTURE AND PROPERTY CORRELATION, SUBSTITUENT EFFECT, FLUORESCENT REAGENT

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