有机化学 ›› 1996, Vol. 16 ›› Issue (6): 548-551. 上一篇    下一篇

研究论文

KF/AL~2O~3催化的羰基与活性亚甲基化合物的缩合反应

高原;史达清;周龙虎;戴桂元   

  1. 徐州师范大学化学系
  • 发布日期:1996-12-25

Condensation reaction of carbonyl with acidic methylene compound catalyzed by potassium fluoride on alumina

GAO YUAN;SHI DAQING;ZHOU LONGHU;DAI GUIYUAN   

  • Published:1996-12-25

在KF/Al~2O~3催化下, 芳香醛与氰乙酸乙酯或氰乙酰胺发生羰基与亚甲基的缩合反应, 得到高产率的缩合产物, 且为E式结构。

关键词: 氰乙酰胺, 其它基金, 缩合反应, 氰乙酸乙酯, 氧化铝, 亚甲基化合物, 芳香族醛, 氟化钾

The carbonyl-methylene condensation reaction of aromatic aldehydes with ethyl cyanoacetate or cyanoacetamide has been carried out smoothly in the presence of potassium fluorides on alumina in high yield of products, and only the E isomers of the products were obtained.

Key words: ALUMINIUM OXIDE, POTASSIUM FLUORIDE, AROMATIC ALDEHYDE, CONDENSATION REACTION

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