有机化学 ›› 2001, Vol. 21 ›› Issue (12): 1122-1125. 上一篇    下一篇

研究论文

二苄基锡二硫代氨基甲酸衍生物的合成、表征和性质

尹汉东;王勇;马春林;张如芬   

  1. 山东省聊城师范学院化学系.
  • 发布日期:2001-12-25

Synthesis, characteriztion and properties of dibenzyltin derivatives of dithiocarbamate

Yin Handong;Wang Yong;Ma Chunlin;Zhang Rufen   

  1. Shandong.
  • Published:2001-12-25

利用二苄基二氯化锡和二硫代氨基甲酸盐反应,合成了13种新的二苄基锡二硫代氨基甲酸衍生物。通过元素分析、红外光谱、核磁共振氢谱和质谱对其结构进行了表征。初步生物活性测试结果表明,该类化合物对KB癌细胞具有一定的抑制活性。

关键词: 二硫代氨基甲酸P, 合成, 结构表征, 波谱分析, 生物活性, 有机锡化合物, 苄基P

Thirteen dibenzyltin derivatives of dithiocarbamate were synthesized by the reaction of dibenzyltin dichloride with dithiocarbamates. Their structures were characterized by elementary analysis, IR, ^1H NMR and MS. Preliminary biological tests showed that some of new compounds were active against KB well line in vitro.

Key words: CARBAMODITHIOIC ACID P, SYNTHESIS, STRUCTURE CHARACTERISTICS, SPECTROMETRIC ANALYSIS, BIOLOGICAL ACTIVITY, ORGANO TIN COMPOUNDS, BENZYL GROUP P

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