有机化学 ›› 2003, Vol. 23 ›› Issue (5): 488-490. 上一篇    下一篇

研究论文

超声辐射下一步法合成2-氨基-3-氰基-4-芳基-7,7-二甲基-5-氧代-5,6,7,8-四氢-4H-苯并[b]吡喃

屠树江;蒋虹;庄启亚;缪春宝;史达清;王香善;高原   

  1. 徐州师范大学化学系;深圳大学化学系
  • 发布日期:2003-05-25

One-Pot Synthesis of 2-Amimo-3-cyano-4-aryl-7,7-dimethyl-5-oxo-5,6, 7,8-tetrahydro-4H-benzo[b]pyran under Ultrasonic Irradiation without Catalyst

Tu Shujiang;Jiang Hong;Zhuang Qiya;Miao Chunbao;Shi Daqing;Wang Xiangshan;Gao Yuan   

  1. Department of Chemistry,Xuzhou Normal University ,Key Laboratory of Biotechnology on Medical Plant of Jiangsu;Department of Chemistry, Shenzhen University
  • Published:2003-05-25

芳醛、丙二腈和5,5-二甲基-1,3-环己二酮在乙二醇中不加任何催化剂经超 声辐射5-7min得2-氨基-3-氰基-4-芳基-7,7-二甲基-5-氧代-4H-5,6,7,8-四氢 苯并[b]吡喃,产率88%—96%.

关键词: 芳香族醛, 丙二腈, 环己二酮 P, 乙二醇, 苯并吡喃 P

A series of 2-amimo-3-cyano-4-aiyl-7, 7-dimethyl-5-oxo-5,6,7, 8- tetrahydro-4//-benzo [ b ] pyran were synthesized by the condensation of arylaldehydes with malononitrile and 5, 5-dimethyl-l, 3- cyclohexanedione under ultrasonic irradiation without catalyst. The structure of the product was determined by IR, 1H NMR spectra, and single crystal X-ray diffraction analysis

Key words: aromatic aldehyde;PROPANEDINITRILE;CYCLOHEXANEDIONE P;ETHANEDIOL, BENZOPYRAN P

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