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有机化学
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有机化学 ›› 2006, Vol. 26 ›› Issue (02): 252-255. 上一篇    下一篇

研究简报

联苯类手性双膦配体的合成方法改进

方春梅，马梦林，郑学丽，郭妤，彭宗海
陈华*，李贤均   

  1. (四川大学化学学院有机金属络合催化研究所 绿色化学及技术教育部重点实验室 成都 610064)
  • 收稿日期:2005-04-11 修回日期:2005-08-23 发布日期:2006-01-21
  • 通讯作者: 陈华

Improvement on the Synthesis of Chiral BiphenylDiphosphine Ligands

FANG Chun-Mei,MA Meng-Lin,ZHENG Xue-Li,GUO Yu,PENG Zong-Hai
CHEN Hua*,LI Xian-Jun   

  1. (Key Laboratory of Green Chemistry and Technology of Ministry of Education, Institute of Homogeneous Cataly-sis,
    Department of Chemistry, Sichuan University, Chengdu 610064)
  • Received:2005-04-11 Revised:2005-08-23 Published:2006-01-21
  • Contact: CHEN Hua

PDF

2055

被引次数

16

从易获得的间溴苯甲醚出发, 利用改进后的方法经六步反应合成了手性双膦配体(R)-和(S)-6,6-二甲氧基-2,2-二(二芳基膦基)-1,1'-联苯[(R)-和(S)-6], 改进后的方法简化了合成步骤, 提高了收率, 可方便地用于在苯环上具有不同取代基的联苯类手性双膦配体衍生物的合成.

关键词: 二芳基双膦, 手性配体, 合成

The chiral diphosphines, R- and S-(6,6'-dimethoxy-2,2'-bis(diarylphosphino)-1,1'-biphenyl, have been prepared with six steps from commercially available 3-bromoanisole by a concise synthetic route. This approach was also an efficient synthetic method for the biphenyl diphosphines with the different diaryl-phosphino group.

Key words: chiral ligand, synthesis, biarylenediphosphine