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有机化学
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有机化学 ›› 2006, Vol. 26 ›› Issue (06): 870-873. 上一篇    下一篇

研究简报

3-芳基-6-对甲苯甲酰氨基均三唑并[3,4-b]-1,3,4-噻二唑的合成及生物活性

张欣，覃章兰*   

  1. (华中师范大学化学学院 武汉 430079)
  • 收稿日期:2005-11-02 修回日期:2005-12-31 发布日期:2006-05-31
  • 通讯作者: 覃章兰

Synthesis and Fungicidal Activity of 3-Aryl-6-(4-Methyl-Benzoylamino)-S-Tria-zolo(3,4-b)-1,3,4-Thiadiazoles

ZHANG Xin,QING Zhang-Lan*   

  1. (Department of Chemistry, Central China Normal University, Wuhan 430079)
  • Received:2005-11-02 Revised:2005-12-31 Published:2006-05-31
  • Contact: QING Zhang-Lan

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利用3-芳基-4-氨基-5-巯基-1,2,4-均三唑和对甲苯甲酰异硫氰酸酯在乙腈中反应, 得到一系列3-芳基-6-对甲苯甲酰氨基均三唑并[3,4-b]-1,3,4-噻二唑, 用1H NMR, IR, MS和元素分析确定了其结构, 并对其进行了抗菌活性测试.

关键词: 均三唑并[3,4-b]-1,3,4-噻二唑, 合成, 抗菌活性

The reaction of 1-amino-5-mercapto-2-(un)substitued phenyl-1,3,4-triazale with p-methylben- zoyl isothiocyanate in the presence of absolute acetonitrile yielded a series of 3-Aryl-6-(4-Methyl-Ben-zoylamino)-S-Triazolo(3,4-b)-1,3,4-Thiadiazoles, with the structures determined by 1H NMR, IR, MS spectra and elemental analysis, and the fungicidal activities were tested.

Key words: synthesis, fungicidal activity, S-triazolo(3,4-b)-1,3,4-thiadiazoles