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有机化学
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有机化学 ›› 2006, Vol. 26 ›› Issue (07): 1001-1003. 上一篇    下一篇

研究简报

2,5-二取代-1,3,4-三唑的合成

雷茂义，邹建平*，饶卫东   

  1. (苏州大学化学化工学院江苏省有机合成重点实验室 苏州 215006)
  • 收稿日期:2005-06-30 修回日期:2006-01-25 发布日期:2006-07-01
  • 通讯作者: 邹建平

Synthesis of 2,5-Disubstituted-1,3,4-triazole Derivatives

LEI Mao-Yi,ZOU Jian-Ping*,RAO Wei-Dong   

  1. (Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineer-ing,
    Suzhou University, Suzhou 215006)
  • Received:2005-06-30 Revised:2006-01-25 Published:2006-07-01
  • Contact: ZOU Jian-Ping

PDF

1102

被引次数

16

以苯甲酰氯、硫氰酸钾和芳胺为起始原料, 合成了1-苯甲酰基-3-芳基硫脲1a～1g, 再与水合肼反应合成了2,5-二取代-1,3,4-三唑2a～2g. 化合物2的结构经IR, 1H NMR和HRMS确证.

关键词: 1-苯甲酰基-3-芳基硫脲, 2,5-二取代-1,3,4-三唑, 合成

2,5-Disubstituted-1,3,4-triazole derivatives were prepared by the reaction of hydrazine hydrate with 1-benzoyl-3-arylthioureas obtained from the reaction of benzoyl chloride, potassium thiocyanate and aniline, and their structures were confirmed by IR, 1H NMR and HRMS spectra.

Key words: 2,5-disubstituted-1,3,4-triazole, synthesis, 1-benzoyl-3-arylthiourea