有机化学 ›› 2008, Vol. 28 ›› Issue (01): 37-43. 上一篇    下一篇

综述与进展

1-茚满酮合成方法研究进展

麻远*,殷巍,赵玉芬   

  1. (清华大学化学系 生命有机磷化学与化学生物学教育部重点实验室 北京 100084)
  • 收稿日期:2007-01-04 修回日期:1900-01-01 发布日期:2008-01-23
  • 通讯作者: 麻远

Progress in Synthesis of 1-Indanones

MA Yuan*, YIN Wei, ZHAO Yu-Fen   

  1. (Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Department of Chemistry,
    Tsinghua University, Beijing 100084)
  • Received:2007-01-04 Revised:1900-01-01 Published:2008-01-23
  • Contact: MA Yuan

1-茚满酮类化合物是许多药物和天然产物合成中的中间体, 有关这类化合物的合成方法仍然不断得到更新. 按照关环位点对于这些合成方法进行了综述, 着重介绍了2000以来的合成新进展.

关键词: 1-茚满酮, 合成, 分子内环化反应

1-Indanones are versatile key intermediates in the synthesis of a number of biologically active compounds. The synthetic methods of 1-indanones are still updating nowadays. The development of the synthetic methods for 1-indanones is reviewed in this paper according to the cyclization sites of the compounds, and the methods developed from 2000 are introduced emphatically.

Key words: synthesis, 1-indanone, intramolecular cyclization