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有机化学
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有机化学 ›› 2008, Vol. 28 ›› Issue (01): 99-103. 上一篇    下一篇

研究论文

2-(1-苯基-1H-四唑-5-硫基)-N-芳基乙酰胺的合成及其生物活性研究

魏太保，李伟，徐蓉，张有明*，高黎明   

  1. (西北师范大学化学化工学院 甘肃省高分子材料重点实验室 兰州 730070)
  • 收稿日期:2007-04-08 修回日期:1900-01-01 发布日期:2008-01-23
  • 通讯作者: 张有明

Synthesis and Biology Activity of 2-(1-Phenyl-1H-tetrazol-5-yl) thio-N-acetamides

WEI Tai-Bao, LI Wei, XU Rong, c*, GAO Li-Ming   

  1. (Gansu Key Laboratory of Polymer Materials, College of Chemistry and Chemical Engineer-ing,
    Northwest Normal University, Lanzhou 730070)
  • Received:2007-04-08 Revised:1900-01-01 Published:2008-01-23
  • Contact: ZHANG You-Ming

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采用微波法通过2-氯乙酰芳胺与1-苯基-1H-四唑-5-硫醇反应合成了一系列2-(1-苯基-1H-四唑-5-硫基)-N-芳基乙酰胺. 其结构经 IR, 1H NMR, 13C NMR 和元素分析表征. 生物活性实验结果表明, 该类化合物在较低浓度下对油菜籽和小麦的生长表现出良好的促进作用.

关键词: 2-(1-苯基-1H-四唑-5-硫基)-N-芳基乙酰胺, 合成, 生物活性

A series of 2-(1-phenyl-1H-tetrazol-5-yl)thio-N-acetamide derivatives were synthesized from 2-chloracetanilide and 1-phenyl-1H-tetrazol-5-thiol under the microwave irradiation and characterized by IR, 1H NMR ,13C NMR spectra and elemental analysis. The plant growth regulating activity tests showed that all compounds had good activity at low concentrations as plant growth regulator.

Key words: systhesis, 2-(1-phenyl-1H-tetrazol-5-yl)thio-N-acetamides, biological activity