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有机化学
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有机化学 ›› 2008, Vol. 28 ›› Issue (07): 1259-1263. 上一篇    下一篇

研究简报

钯碳催化下以甲酰肼为还原剂的卤代芳烃还原偶联反应研究

朱雯芳; 乔江彬 ; 卓广澜*   

  1. (浙江理工大学应用化学系 杭州 310018)
  • 收稿日期:2007-10-20 修回日期:2007-12-18 发布日期:2008-07-28
  • 通讯作者: 卓广澜

Pd/C-Catalyzed Reductive Coupling of Aryl Halides Using Formic Hydrazide as Reducing Agent

ZHU, Wen-; QIAO, Jiang-Bin ; ZHUO, Guang-Lan*   

  1. (Department of Applied Chemistry, Zhejiang Sci-Tech University, Hangzhou 310018)

  • Received:2007-10-20 Revised:2007-12-18 Published:2008-07-28
  • Contact: ZHUO, Guang-Lan

PDF

759

被引次数

10 | 1

在Pd/C催化下, 以甲酰肼为还原剂, 卤代芳烃通过还原偶联反应能高选择性地合成相应的联苯化合物. 具有不同取代基的卤代芳烃的还原偶联反应产率在52%～94%之间.

关键词: 卤代芳烃, 甲酰肼, Pd/C, 还原偶联反应, 联苯衍生物

The reductive coupling of aryl halides to form the corresponding biaryls was effected with high selectivity in water, using formic hydrazide as a reducing agent in the presence of a catalytic amount of Pd/C. Various substituted aryl halides proceed smoothly to afford the corresponding biaryls with good yields in the range of 52%～94%.

Key words: aryl halide, reductive coupling reaction, formic hydrazide, Pd/C, biaryl