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有机化学
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有机化学 ›› 2009, Vol. 29 ›› Issue (10): 1499-1507. 上一篇    下一篇

综述与进展

手性氮杂卡宾金属络合物的合成及其在不对称催化反应中的应用

古丽娜a,b  祝冠彬a  宋海斌*,a  自国甫*,b   

  1. a南开大学元素有机化学国家重点实验室 天津 300071, b北京师范大学化学学院 北京 100875
  • 收稿日期:2009-01-07 修回日期:2009-02-17 发布日期:2009-03-09

Progress in Preparation of Chiral NHC-Metal Complexes and Their Use as Catalysts in Asymmetric Reactions

Gu, Lina a,b   Zhu, Guanbina   Song, Haibin*,a   Zi, Guofu*,b   

  1. a State Key Laboratory of Elemento-organic Chemistry, Nankai University, Tianjin 300071, b College of Chemistry, Beijing Normal University, Beijing 100875
  • Received:2009-01-07 Revised:2009-02-17 Published:2009-03-09

PDF

2336

被引次数

19

手性氮杂卡宾金属络合物在多种催化反应中得到了广泛的应用, 并取得了很好的研究成果. 综述了手性氮杂卡宾金属络合物的合成以及它们在催化不对称反应中的应用研究进展, 如催化α,β-不饱和酮的1,4-加成反应、酮的氢硅烷化反应、烯烃的氢化反应和烯烃的复分解反应等.

关键词: 手性氮杂卡宾金属络合物, 合成, 不对称催化反应

Organometallic complexes with chiral nitrogen-heterocyclic-carbenes (NHC) have been extensively used in catalytic reactions with excellent catalytic activity. This review summarizes the progress in the preparation of the chiral NHC-metal complexes and their use as catalysts in asymmetric reactions such as asymmetric 1,4-addition of α,β-unsaturated ketones, hydrosilylation of ketones, hydrogenation of olefins and olefin metathesis reaction, etc.

Key words: chiral NHC-metal complex, synthesis, enantioselective catalysis