有机化学 ›› 2001, Vol. 21 ›› Issue (7): 493-504. 上一篇    下一篇

研究论文

抗癌药物紫杉醇的全合成-Nicolaou法合合成紫杉醇的剖析

徐亮;王锋鹏   

  1. 四川大学华丁药学院天然药物化学教研室
  • 发布日期:2001-07-25

Total synthesis of taxol develped by nicolaou

Xu Liang;Wang Fengpeng   

  • Published:2001-07-25

介绍和剖析了用Micolaou法全合成紫杉醇的方法,包括合成的战略和路线,关键反应和保护基的应用等。

关键词: 抗癌药, 紫杉醇, Nicolaou法, 药理

The totoal synthesis of taxol developed by Nicolaou, including the synthetic strategy and routes, model reaction studies, key reactions and application of the protective groups is analysed.

Key words: ANTICARCINOGEN, TAXUS CHENSIS, PHARMACOLOGY

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