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有机化学
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有机化学 ›› 1999, Vol. 19 ›› Issue (2): 184-189. 上一篇    下一篇

研究论文

从4-戊烯醛经增碳反应合成5-己烯酸甲酯类化合物

陈立功;李阳;孟Yi;李渊;吕萌;罗会兵;王勇   

  1. 天津大学化工学院应用化学与精细化工系
  • 发布日期:1999-04-25

Synthesis of methyl 5-hexenates by homologation of 4-pentenals

Chen Ligong;Li Yang;MENG ;Li Yuan;Lu Meng;Luo Huibing;Wang Yong   

  • Published:1999-04-25

通过4,8,12-三甲基-4,8,12-三烯醛(1)类四戊烯醛衍生物的增一碳反应合成了5,9,13-三甲基-5,9,13-十四三烯醛甲酯(3)及5-己烯酸甲酯衍生物(7-9)。用甲氧基甲基三苯基膦处理4-戊烯醛类化合物生成烯基醚,PCC氧化所生成的烯醚则得到标题化合物,5-己烯酸甲酯类化合物。

关键词: Wittig反应, 氧化反应, 戊烯醛, 己烯酸甲酯, 增碳反应

Methyl 5, 9, 13-trimethylbutadeca-5, 9, 13-trienoate (3) and methyl 5-hexenates (7-9) were synthesized by homologation of 4, 8, 12- trimethyl-4, 8, 12-tridecatrienal (1) and 4-pentenals. Thus, treatment of 4-pentenals with methoxy methylenetriphenylphosphin afforded a mixture of cis- and trans- enol ethers, which were oxidized by PCC to give methyl 5-hexenates.

Key words: OXIDATION REACTION

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