有机化学 ›› 2003, Vol. 23 ›› Issue (10): 1146-1148. 上一篇    下一篇

研究论文

KF-Al_2O_3催化下达米酮与查尔酮的麦克尔加成反应

王苏惠;王香善;史达清;屠树江   

  1. 徐州师范大学化学系
  • 发布日期:2003-10-25

Michael Addition Reaction of Dimedone and Chalcone Catalyzed by KF/Al_2O_3

Wang Suhui;Wang Xiangshan;Shi Daqing;Tu Shujiang   

  1. Department of Chemistry, Xuzhou Normal University
  • Published:2003-10-25

5,5-二甲基-1,3-环己二酮(达米酮)、1,3-二芳基-2-丙烯-1-酮(查尔酮 )在KF-Al_2O_3催化下,在DMF中进行麦克尔加成反应,生成产物为1,3-二芳基- 3-(5,5-二甲基-3-羟基-2-环己烯-1-酮-2-基)-1-丙酮,产率良好。

关键词: 查尔酮, 氟化钾, 氧化铝, 迈克尔加成反应, 二甲基甲酰胺

1,3-Diaryl-3-(5,5-dimethyl-3-hydi-oxy-2-cyclohexene-1-one-2-yl)-1- acetones have been synthesized in good yields by the Michael addition reaction of 5,5-dimethyl-1, 3-cyclohexanedione (dimedone) with 1,3- diaiyl-2-propen-1-one (chalcone) in DMF catalyzed by KF/Al_2O_3.

Key words: chalone;POTASSIUM FLUORIDE;ALUMINIUM OXIDE;MICHAEL ADDITION REACTION, DMF

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