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有机化学
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有机化学 ›› 2007, Vol. 27 ›› Issue (9): 1159-1161. 上一篇    下一篇

研究简报

海洋放线菌Streptomyces sp. V5产生的一个新的八元环内酯

陈光英*,a，朱峰b，林永成c   

  1. (a海南师范大学化学系 海口 571158)
    (b佛山科学技术学院化学与化工系 佛山 528000)
    (c中山大学化学与化学工程学院 广州 510275)
  • 收稿日期:2006-06-23 修回日期:1900-01-01 发布日期:2007-08-30
  • 通讯作者: 陈光英

A Novel 8-Membered Macrolide Produced by a Ma-rine-DerivedActinomycete Streptomyces sp. V5

CHEN Guang-Ying*,a,ZHU Fengb,LIN Yong-Chengc   

  1. (a Department of Chemistry, Hainan Normal University, Haikou 571158)
    (b Department of Chemistry & Chemical Engineering, Foshan Univer-sity, Foshan 528000)
    (c School of Chemistry and Chemical Engineering, Zhongshan University, Guangzhou 510275)
  • Received:2006-06-23 Revised:1900-01-01 Published:2007-08-30
  • Contact: CHEN Guang-Ying

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海洋放线菌Streptomyces sp. V5分离自南中国海红树根部土壤, 从其培养液分离获得一个新的八元环内酯octalactin C (A), 以及四个已知化合物2-甲基-3-呋喃甲酸(B)、环(脯-亮)二肽(C)、环(丙-缬)二肽(D)和尿嘧啶(E). 通过完整的波谱数据解析了它们的结构.

关键词: 海洋放线菌, Streptomyces sp., 代谢产物, 大环内酯

A novel 8-membered macrolide, designated as octalactin C (A), together with four known com-pounds, 2-methylfuran-3-carboxylic acid (B), cyclo-(Pro-Leu) (C), cyclo-(Ala-Val) (D) and uracil (E), were isolated from the culture broth of Streptomyces sp. V5 which was isolated from the rhizosphere soil of mangrove root on the South China Sea coast. Their structures were determined by comprehensive spectroscopic methods.

Key words: macrolide, metabolite, Streptomyces sp., marine actinomycete