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有机化学
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有机化学 ›› 2005, Vol. 25 ›› Issue (11): 1372-1380. 上一篇    下一篇

综述与进展

有机过氧化物中过氧键的建立(引入)方法

金红霞，伍贻康*   

  1. (中国科学院上海有机化学研究所 生命有机化学国家重点实验室 上海 200032)
  • 收稿日期:2005-02-01 修回日期:2005-07-04 发布日期:2005-10-30
  • 通讯作者: 伍贻康

Methods for Constructing the Peroxy Bonds of Organic Peroxides

JIN Hong-Xia,WU Yi-Kang*   

  1. (State Key Laboratory of Bio-organic & Natural Products Chemistry, Shanghai Institute of Organic Chemis-try,
    Chinese Academy of Sciences, Shanghai 200032)
  • Received:2005-02-01 Revised:2005-07-04 Published:2005-10-30
  • Contact: WU Yi-Kang

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被引次数

5

有机过氧化物目前已发展成非常重要的一类抗疟药物. 形成/引入过氧键是合成有机过氧化物的关键步骤和难点所在. 对合成有机过氧化物时常见的建立或引入过氧键的方法、各方法的适用范围及优劣所在作了简要的综述.

关键词: 有机过氧化物, 合成, 激发态氧, 自由基, 基态氧

Organic peroxides now have become a very important class of antimalarial agents. Construction/ introduction of the peroxy bond is the key (and the most difficult) step in the synthesis of organic peroxides. In this paper the methods of constructing/introducing the peroxy bond of organic peroxides are reviewed. The advantage, scope and limitations of each methods are also briefly discussed.

Key words: synthesis, singlet oxygen, organic peroxide, triplet oxygen