有机化学 ›› 2005, Vol. 25 ›› Issue (9): 1116-1120. 上一篇    下一篇

研究简报

2-(苯并噻唑-2-基硫代)-1-(2,3,4-三甲氧基苯基)乙酮肟酯和肟醚新化合物合成与抗烟草花叶病毒活性研究

杨松1,2,宋宝安*,1,2,刘新华2,逄丽丽2
金林红1,2,汪华2,胡德禹1,2,刘刚1, b   

  1. (1教育部绿色农药和农业生物工程重点实验室 贵阳 550025)
    (2贵州大学精细化工研究开发中心 贵阳 550025)
  • 收稿日期:2004-09-05 修回日期:2005-03-26 发布日期:2005-08-24
  • 通讯作者: 宋宝安

Synthesis and Anti-TMV Activity of 2-(Benzo[d]thiazol-2-yl-thio)-1- (2,3,4-trimethoxyphenyl) Ethanoxime Ester and Ether Deriva-tivies

YANG, Song1,2 SONG, Bao-An*,1,2 LIU, Xin-Hua2 PANG, Li-Li2 JIN, Lin-Hong1,2
WANG, Hua2 HU, De-Yu1,2 LIU, Gang1,

  1. (1 Key Laboratory of Green Pesticide and Agriculture Bioengineering, Ministry of Educa-tion, Guiyang 550025)
    (2 Research and Development Center for Fine Chemicals, Guizhou University, Guiyang 550025)
  • Received:2004-09-05 Revised:2005-03-26 Published:2005-08-24
  • Contact: SONG, Bao-An

首次合成了5个2-(苯并噻唑-2-基硫代)-1-(2,3,4-三甲氧)苯乙酮肟酯和6个肟醚新化合物, 并经过元素分析、红外光谱、核磁共振氢谱对其结构进行了表征. 初步生物活性测试表明, 部分化合物具有一定抗烟草花叶病毒活性.

关键词: 酯, 醚, 合成, 苯并噻唑, 2,3,4-三甲氧基苯乙酮肟

Five new 2-(benzo[d]thiazol-2-ylthio)-1-(2,3,4-trimethoxyphenyl) ethanoxime esters and six new ethers were synthesized and characterized by elemental analysis, IR and 1H NMR spectra. The bioassay of some compounds showed that they had moderate anti-TMV activity.

Key words: ether, 2,3,4-trimethoxyacetophenoxime, synthesis, ester, benzothiazol