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有机化学
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有机化学 ›› 2007, Vol. 27 ›› Issue (04): 524-527. 上一篇    下一篇

研究简报

具有生物活性的芳香族腙类衍生物的合成与表征

王建平*,a， 付永举b，尹卫平b，王建革a，秦建华a   

  1. (a洛阳师范学院化学系 洛阳 471022)
    (b河南科技大学化工与制药学院 洛阳 471003)
  • 收稿日期:2006-08-22 修回日期:1900-01-01 发布日期:2007-03-29
  • 通讯作者: 王建平

Synthesis and Characterization of Biological Active Hydrazone Derivatives

WANG Jian-Ping*,a, FU Yong-Jub, YIN Wei-Pingb, WANG Jian-Gea, QIN Jian-Huaa   

  1. (a Department of Chemistry, Luoyang Normal University, Luoyang 471022)
    (b Chemical Engineering & Pharmaceutics College, Henan University of Science and Technology, Luoyang 471003)
  • Received:2006-08-22 Revised:1900-01-01 Published:2007-03-29
  • Contact: WANG Jian-Ping

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1610

被引次数

56 | 10

在冰盐浴条件下, 芳香族重氮盐与活泼亚甲基化合物反应, 合成了六种新芳香族腙类衍生物. 产物经IR, 1H NMR, 13C NMR, 元素分析表征, 其中3b和3e经X射线单晶衍射测定, 确认了其化学结构.

关键词: 活泼亚甲基化合物, 合成, 腙, 芳香族重氮盐

Six kinds of phenyl hydrazones were synthesized by the reaction of ice bath using aromatic diazonium salt and active methylene compounds. The products were characterized via IR, 1H NMR, 13C NMR spectra and elemental analysis as well as single-crystal X-ray diffraction analysis of 3b and 3e.

Key words: synthesis, aromatic diazonium salt, active methylene compound, hydrazone