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有机化学
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有机化学 ›› 2007, Vol. 27 ›› Issue (04): 528-531. 上一篇    下一篇

研究简报

无溶剂NH2SO3H催化下超声促进环酮与芳香醛的Aldol缩合

曾鸿耀, 尹述凡*，李颖   

  1. (四川大学化学学院 成都 610064)
  • 收稿日期:2006-03-27 修回日期:1900-01-01 发布日期:2007-03-29
  • 通讯作者: 尹述凡

Adol Condensation of Cycloalkanones and Aldehydes Catalyzed by NH2SO3H under Solvent-Free Conditions and Ultrasound Irradiation

ZENG Hong-Yao, YIN Shu-Fan*, LI Ying   

  1. (Department of Chemistry, Sichuan University, Chengdu 610064)
  • Received:2006-03-27 Revised:1900-01-01 Published:2007-03-29
  • Contact: YIN Shu-Fan

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以NH2SO3H作催化剂, 在无溶剂条件下用超声技术合成了一系列α,α'-双亚苄基环酮衍生物, 反应在15～45 min内完成, 产率76%～92%, 后处理简便, 且对环境友好.

关键词: 无溶剂, 芳香醛, 环烷酮, aldol缩合, 超声辐射

Using NH2SO3H as catalyst, a series of α,α'-bis(substituted benzylidene)cycloalkanone derivatives were synthesized by cross aldol condensations of cycloalkanones with aldehydes under solvent-free conditions and ultrasound irradiation in 15～45 min with 76%～92% yields. Compared with traditional method, this method was more convenient and environmental friendly.

Key words: aromatic aldehyde, ultrasound irradiation, cycloalkanone, solvent-free, aldol condensation