SIOC English
有机化学
高级检索

有机化学 ›› 2010, Vol. 30 ›› Issue (06): 928-932. 上一篇    下一篇

研究简报

5(4H)-吡啶酮并氧化呋咱及其核苷衍生物的合成及结构表征

杜杨*,1，许雯1，姚其正2，刘祖亮1   

  1. 1南京理工大学化工学院 南京 210014
    2中国药科大学药学院 南京 210009
  • 收稿日期:2009-10-09 修回日期:2009-12-30 发布日期:2010-02-01
  • 通讯作者: 杜杨 E-mail:duy@mail.njust.edu.cn

Synthesis and Characterization of 4H-Pyridofuroxan-5-one and Its Nucleotide Derivative

Du Yang*,1 Xu Wen1 Yao Qizheng2 Liu Zuliang1   

  1. 1 School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210014)
    (2 School of Pharmacy, China Pharmaceutical University, Nanjing 210009
  • Received:2009-10-09 Revised:2009-12-30 Published:2010-02-01

PDF

1157

设计了一个新化合物--5(4H)-吡啶酮并氧化呋咱(4H,5H-[1,2,5]噁二唑[3,4-b]吡啶-5-酮-1-氧化物), 对它的合成方法及四乙酰核糖核苷衍生物的合成进行了研究. 合成产物及中间体经1H NMR、质谱和元素分析进行了结构鉴定.

关键词: 5(4H)-吡啶酮并氧化呋咱, 氧化呋咱, 核苷

A new compound, 4H-pyridofuroxan-5-one (4,5-dihydro-[1,2,5]oxadiazolo[3,4-b]pyridine- 5-one 1-oxide), and its nucleotide derivative of tetraacetoxy D-ribose, were synthesized, and their structures as well as intermediates of each reactions were confirmed by 1H NMR, MS techniques and elemental analysis.

Key words: 4H-pyridofuroxan-5-one, furoxan, nucleotide