有机化学 ›› 2011, Vol. 31 ›› Issue (06): 897-900. 上一篇    下一篇

研究简报

微波辐射下2-硝基芴与芳香醛的Knoevenagel反应

胡卫兵*,冯驸,黎云攀,周红艳,王辉,田大听   

  1. (湖北民族学院化学与环境工程学院 恩施 445000)
  • 收稿日期:2010-09-10 修回日期:2010-12-23 发布日期:2011-01-30
  • 通讯作者: 冯驸 E-mail:fu.feng@yahoo.com.cn

Microwave-Assisted Knoevenagel Reaction of 2-Nitrofluorene with Aromatic Aldehyde

HU Wei-Bing, FENG Fu, LI Yun-Pan, ZHOU Hong-Yan, WANG Hui, TIAN Da-Ting   

  1. (School of Chemistry and Environmental Engineering, Hubei Institute for Nationalities, Enshi 445000)
  • Received:2010-09-10 Revised:2010-12-23 Published:2011-01-30
  • Contact: feng fu1 E-mail:fu.feng@yahoo.com.cn

以2-硝基芴和芳香醛为原料, 在碱性条件下, 微波辐射(500 W)反应5~8 min, 非常方便地合成了系列未见文献报道的Knoevenagel反应产物, 该方法操作简单、产率较高(78%~89%). 其结构经IR, 1H NMR, MS和元素分析进行了表征. 对化合物3a3d进行了紫外吸收和荧光测定, 结果显示这些化合物具有荧光特性.

关键词: 2-硝基芴, Knoevenagel, 微波合成, 荧光特性, 紫外吸收光谱

A series of novel Knoevenagel products of 2-nitrofluorene to a series of aromatic aldehydes were obtained in the presence of sodium hydroxide under microwave irradiation (500 W) within short reaction times (5~8 min) in high yields (78%~89%). The structures of the products were characterized by IR, 1H NMR, MS techniques and elemental analysis. The UV absorption and fluorescent spectra of compounds 3a3d were detected and showed that they had fluorescence.

Key words: 2-nitrofluorene, Knoevenagel, microwave-assisted, fluorescent property, UV absorption