有机化学 ›› 2019, Vol. 39 ›› Issue (5): 1424-1428.DOI: 10.6023/cjoc201812007 上一篇    下一篇

所属专题: 碳氢活化合辑2018-2019

研究论文

通过电化学脱氢N—N偶联合成四取代肼化合物

冯恩祺, 侯中伟, 徐海超   

  1. 厦门大学化学化工学院 厦门 361005
  • 收稿日期:2018-12-04 修回日期:2018-12-27 发布日期:2019-01-18
  • 通讯作者: 徐海超 E-mail:haichao.xu@xmu.edu.cn
  • 基金资助:

    国家自然科学基金(No.21672178)、国家基础科学人才培养(No.J131002)资助项目.

Electrochemical Synthesis of Tetrasubstituted Hydrazines by Dehydrogenative N-N Bond Formation

Feng Enqi, Hou Zhongwei, Xu Haichao   

  1. College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005
  • Received:2018-12-04 Revised:2018-12-27 Published:2019-01-18
  • Contact: 10.6023/cjoc201812007 E-mail:haichao.xu@xmu.edu.cn
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21672178) and the National Foundation for Fostering Talents in Basic Science (No. J1310024).

通过电氧化二级芳胺合成了一系列四取代肼化合物.该电合成反应采用简单的装置如单室电解槽和恒电流电解,且无需过渡金属催化剂和氧化试剂,并可放大至克级规模.

关键词: 有机电合成, 电氧化, 脱氢偶联, 四取代肼

An electrochemical synthesis of tetrasubstituted hydrazines through dehydrogenative dimerization of secondary amines has been developed. The reactions are conducted in a simple undivided cell with constant current. The use of electricity to promote the reactions obviates the need for transition metal catalysts and oxidizing reagents, providing an efficient and sustainable access to tetrasubstituted hydrazines with diverse electronic properties.

Key words: organic electrosynthesis, anodic oxidation, dehydrogenative coupling, tetrasubstituted hydrazines