有机化学 ›› 2020, Vol. 40 ›› Issue (2): 462-469.DOI: 10.6023/cjoc201909005 上一篇    下一篇

研究论文

钯催化氧化/水解2-炔基芳基叠氮一锅法合成2-苯甲酰胺基苯甲酸

圣戎, 李萍, 周志强, 胡贵文, 张小祥   

  1. 南京林业大学化工学院 江苏省生物质绿色燃料与化学品重点实验室 南京 210037
  • 收稿日期:2019-09-02 修回日期:2019-09-27 发布日期:2019-10-12
  • 通讯作者: 张小祥 E-mail:zhangxiaoxiang@njfu.edu.cn
  • 基金资助:
    江苏省研究生创新计划(No.KYCX18_0967)、国家自然科学基金(No.21302096)、江苏省自然科学基金(No.BK20171449)、江苏高校“青蓝工程”资助项目.

Pd-Catalyzed One-Pot Oxidation/Hydrolysis for the Synthesis of 2-Benzoylaminobenzoic Acids from 2-Alkynyl Arylazides

Sheng Rong, Li Ping, Zhou Zhiqiang, Hu Guiwen, Zhang Xiaoxiang   

  1. College of Chemical Engineering, Jiangsu Key Laboratory of Biomass-based Green Fuels and Chemicals, Nanjing Forestry University, Nanjing 210037
  • Received:2019-09-02 Revised:2019-09-27 Published:2019-10-12
  • Supported by:
    Project supported by the Postgraduate Research & Practice Innovation Program of Jiangsu Province (No. KYCX18_0967), the National Natural Science Foundation of China (No. 21302096), the Natural Science Foundation of Jiangsu Province (No. BK20171449) and the Qing Lan Project.

描述了通过钯催化2-炔基芳基叠氮一锅法氧化/水解制备2-苯甲酰胺基苯甲酸的合成方法.在温和的反应条件下,反应以良好至极好的产率完成.

关键词: 钯催化, 一锅化反应, 氧化, 水解, 2-苯甲酰氨基苯甲酸

A synthetic method to prepare 2-benzoylaminobenzoic acids via Pd-catalyzed one-pot oxidation/hydrolysis from 2-alkynyl arylazides is described. The reaction was accomplished in good to excellent yields under mild reaction conditions.

Key words: Pd-catalyzed, one-pot reaction, oxidation, hydrolysis, 2-benzoylaminobenzoic acids