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有机化学
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有机化学 ›› 2004, Vol. 24 ›› Issue (2): 227-230. 上一篇    下一篇

研究简报

N′-叔丁基-N-取代酰基(硫)脲类化合物的合成及生物活性测定

薛思佳, 柯少勇*, 段李平   

  1. 上海师范大学生命与环境科学学院 上海 200234
  • 收稿日期:2003-05-26 修回日期:2003-07-07 接受日期:2003-09-01 发布日期:2022-09-20
  • 基金资助:
    上海市科委2001科学发展基金(No. BL200116)资助项目

Synthesis and Bioactivity of N′-tert-Butyl-N-substituted Acyl(thio)urea Derivatives

XUE, Si-Jia, KE, Shao-Yong*, DUAN, Li-Ping   

  1. College of Life and Environment Science, Shanghai Normal University, Shanghai 200234
  • Received:2003-05-26 Revised:2003-07-07 Accepted:2003-09-01 Published:2022-09-20
  • Contact: * E-mail: keshaoyong@163.com

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将叔丁基引入到酰基(硫)脲骨架中,设计合成了8个未见文献报道的N′-叔丁基-N-取代酰基脲及N′-叔丁氨基羰基-N-取代酰基硫脲类化合物,其结构经元素分析、IR和1H NMR得到确证.初步的生物活性测试结果表明部分化合物具有较好的除草活性.

关键词: N′-叔丁基-N-取代酰基脲, N′-叔丁氨基羰基-N-取代酰基硫脲, 合成, 生物活性

Eight new N′-tert-butyl-N-substituted acylurea and N′-tert-butylaminocarbonyl-N-substituted acylthiourea derivatives were synthesized and characterized. The structures of these compoundswere determined by 1H NMR, IR and elemental analysis. The preliminary biologic tests show that some of the title compounds have excellent inhibitory activity against weeds.

Key words: N′-tert-butyl-N-substituted acylurea, N′-tert-butylaminocarbonyl-N-substituted acylthiourea, synthesis, biological activity