过渡金属催化远程二烯的不对称迁移烯丙位碳氢键活化

doi:10.6023/cjoc202406047

摘要/Abstract

烯丙位碳氢键的不对称活化转化是具有重要价值和挑战性的一个研究方向。不同于传统的直接脱氢策略,过渡金属催化共轭二烯参与的迁移烯丙基取代反应是近年来发展起来的新的烯丙位碳氢键不对称活化转化的思路。本文综述了该领域的发展历程和进展,讨论了相关的机制过程,并将其按照金属催化剂和产物类型进行了介绍。

关键词: 远程二烯, 金属迁移, 迁移烯丙基取代, 烯丙位碳氢键活化, 不对称合成

Asymmetric allylic C-H functionalization is a valuable and challenging research area. Different from the conventional direct allylic C-H cleavage strategy, transition metal-catalyzed migratory allylic substitution of remote dienes has emerged as a new route to achieve allylic C-H functionalization enantioselectively. This review provides a detailed summary of the development and advance of this strategy, introduces the related mechanistic processes, and discusses the area based on the types of catalysts and products.

Key words: Remote dienes, Metal walking, Migratory allylic substitution, Allylic C-H bond functionalization, Asymmetric synthesis

引用此文

张经明, 何智涛. 过渡金属催化远程二烯的不对称迁移烯丙位碳氢键活化[J]. 有机化学, doi: 10.6023/cjoc202406047.

Jing-Ming Zhang, Zhi-Tao He. Transition metal-catalyzed asymmetric migratory allylic C-H functionalization of remote dienes[J]. Chinese Journal of Organic Chemistry, doi: 10.6023/cjoc202406047.

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