Efficient One-Pot Synthesis of 1,4-Dihydropyridino[3,2-c]coumarins

doi:10.6023/cjoc201309025

Chin. J. Org. Chem. ›› 2014, Vol. 34 ›› Issue (4): 783-787.DOI: 10.6023/cjoc201309025 Previous Articles Next Articles

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1,4-二氢吡啶并[3,2-c]香豆素类衍生物的有效合成

王道林^a, 董哲^a, 刘忠^b, 赵伟^a, 杨菲菲^a

a 辽宁省功能化合物合成与应用重点实验室渤海大学化学化工与食品安全学院锦州 121003;
b 吉林省石油化工设计研究院长春 130021

收稿日期:2013-09-16 修回日期:2013-12-04 发布日期:2013-12-13
通讯作者: 王道林 E-mail:wangdaolin@sina.com
基金资助:
辽宁省科技厅（No. 2011220022）资助项目.

Efficient One-Pot Synthesis of 1,4-Dihydropyridino[3,2-c]coumarins

Wang Daolin^a, Dong Zhe^a, Liu Zhong^b, Zhao Wei^a, Yang Feifei^a

a Key Laboratory of Synthesis & Application of Functional Compound, College of Chemistry, Chemical Engineering & Food Safety, Bohai University, Jinzhou 121003;
b Jilin Research Institute of Petrochemical Technology, Changchun 130021

Received:2013-09-16 Revised:2013-12-04 Published:2013-12-13
Supported by:
Project supported by the Science and Technology Department of Liaoning Province (No. 2011220022).

Abstract

Efficient one-pot synthesis of 1,4-dihydropyridino[3,2-c]coumarines was obtained starting from 4-aminocou-marin, aromatic aldehydes and phenylacetylene via imino-Diels-Alder reaction in the presences of molecular iodine as a catalyst in good yields. All of above compounds have been confirmed by NMR, IR, MS spectra and elemental analysis.

Key words: 4-aminocoumarins, phenylacetylene, 1,4-dihydropyridino[3,2-c]coumarine, imino-Diels-Alder reaction, iodine, synthesis

Cite this article

Wang Daolin, Dong Zhe, Liu Zhong, Zhao Wei, Yang Feifei. Efficient One-Pot Synthesis of 1,4-Dihydropyridino[3,2-c]coumarins[J]. Chin. J. Org. Chem., 2014, 34(4): 783-787.

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1,4-二氢吡啶并[3,2-c]香豆素类衍生物的有效合成

Efficient One-Pot Synthesis of 1,4-Dihydropyridino[3,2-c]coumarins

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