Chin. J. Org. Chem. ›› 2014, Vol. 34 ›› Issue (3): 605-609.DOI: 10.6023/cjoc201310006 Previous Articles     Next Articles

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烯基溴化合物的合成方法研究进展

张文生a, 许文静a, 匡春香b   

  1. a 焦作师范高等专科学校理工学院 焦作 454001;
    b 同济大学化学系 上海 200092
  • 收稿日期:2013-10-09 修回日期:2013-11-06 发布日期:2013-11-20
  • 通讯作者: 张文生,匡春香 E-mail:tongjizws@163.com
  • 基金资助:

    国家自然科学基金(No. 21272174);河南省科技厅基础和前沿研究计划(Nos. 132300410206,132300410167);焦作市科技局科技计划(No. 2012017)资助项目.

Research Advances in the Synthetic Methods of Vinyl Bromides

Zhang Wenshenga, Xu Wenjinga, Kuang Chunxiangb   

  1. a School of Technology, Jiaozuo Teachers College, Jiaozuo 454001;
    b Department of Chemistry, Tongji University, Shanghai 200092
  • Received:2013-10-09 Revised:2013-11-06 Published:2013-11-20
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21272174), the Foundation of He'nan Scientific and Technological Committee (Nos. 132300410206, 132300410167) and the Foundation of Jiaozuo Scientific and Technological Bureau (No. 2012017).

Vinyl halides (1-halo-1-alkenes), especially vinyl bromides, represent a kind of organic synthetic blocks, which play important roles in the construction of polysubstituted alkenes through transition metal-catalyzed C—C cross-coupling reactions. Consequently, there have been much attentions in facile, efficient methods of preparing vinyl bromides. According to the types of the synthetic substrates used in the literatures, newly reported means on the synthesis of vinyl bromides in recent years are surveyed. The synthetic substrates involved in these new approaches include ketones, alkynes, propargylic alcohols, vinyl triflates, 3-aryl-2,3-dibromopropionic acids, benzyl bromides, acrylic acids, cyclopropenes and allylic alcohol derivatives, etc.

Key words: vinyl bromide, synthesis, stereoselectivity, regioselectivity