Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (11): 3738-3747.DOI: 10.6023/cjoc202003022 Previous Articles     Next Articles

Special Issue: 有机电合成虚拟专辑 创刊四十周年专辑


王向阳a, 徐学涛a, 王振华b, 方萍b, 梅天胜b   

  1. a 五邑大学生物科技与大健康学院 广东江门 529020;
    b 中国科学院上海有机化学研究所 金属有机化学国家重点实验室 分子合成科学卓越中心 上海 200032
  • 收稿日期:2020-03-09 修回日期:2020-05-24 发布日期:2020-05-28
  • 通讯作者: 方萍, 梅天胜;
  • 基金资助:

Advances in Asymmetric Organotransition Metal-Catalyzed Electrochemistry

Wang Xiangyanga, Xu Xuetaoa, Wang Zhenhuab, Fang Pingb, Mei Tianshengb   

  1. a School of Biotechnology and Health Science, Wuyi University, Jiangmen, Guangzhou 529020;
    b State Key Laboratory of Organometallic Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
  • Received:2020-03-09 Revised:2020-05-24 Published:2020-05-28
  • Supported by:
    Project supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (No. XDB20000000), the National Natural Science Foundation of China (Nos. 91956112, 21572245, 21772222, 21772220), and the Program of Shanghai Science and Technology Committee of Shanghai (Nos. 17JC1401200, 18JC1415600).

The recent developments in asymmetric organotransition metal-catalyzed electrochemistry (AOMCE) are summarized. AOMCE processes can be divided into oxidative and reductive variants. In terms of oxidations, asymmetric functionalization of olefins, oxidative kinetic resolution of secondary alcohols or aldehydes, and asymmetric C—H functionalization reactions have been developed. Reductive processes discussed include asymmetric electrochemical carboxylation with carbon dioxide, asymmetric electrochemical decarboxylation, and asymmetric reductive coupling reactions. The combination of chiral ligands, transition-metal catalysts, and electrochemistry provides a novel angle by which to address the longstanding fundamental challenge of stereoinduction in traditional electrochemical organic synthesis.

Key words: asymmetric organotransition metal-catalyzed electrochemistry, electrochemical organic synthesis, asymmetric catalysis