Chinese Journal of Organic Chemistry ›› 2023, Vol. 43 ›› Issue (10): 3470-3490.DOI: 10.6023/cjoc202307017 Previous Articles     Next Articles

Special Issue: 有机硅化学专辑-2023


李奇阳, 张海燕, 刘文博*()   

  1. 武汉大学化学与分子科学学院 武汉 430072
  • 收稿日期:2023-07-16 修回日期:2023-08-22 发布日期:2023-08-30
  • 基金资助:
    国家重点研发计划(2022YFA1502902); 国家自然科学基金(22222111); 国家自然科学基金(21971198)

Research Progress in Transition-Metal-Free C—Si Bond Formation

Qiyang Li, Haiyan Zhang, Wenbo Liu()   

  1. College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072
  • Received:2023-07-16 Revised:2023-08-22 Published:2023-08-30
  • Contact: *E-mail:
  • Supported by:
    National Key R&D Program of China(2022YFA1502902); National Nature Science Foundation of China(22222111); National Nature Science Foundation of China(21971198)

Organosilicons are widely used in many chemistry related fields. Given its important role, the chemical syntheses of organosilicon compounds have received considerable attention. Due to outstanding advantages in cost and environmental friendliness, transition-metal-free C—Si bond formation has been widely studied in the past decades and has been emerged as an important alternative to transition-metal-catalyzed C—Si cross-coupling. In this review, the recent developed methods of carbon-silicon bond formation under transition-metal-free conditions are summarized. The discussion is organized according to catalysts (acid catalysis, base catalysis, and radical initiation) and the types of C—Si bonds that formed. In addition, mechanistic discussions of representative reactions and a prospect for future development in this field are also briefly included.

Key words: transition-metal-free, C—Si bond formation, organosilicons, green chemistry