Synthesis of 2-Aryl-5-[4'-(2,2,6,6-tetramethyl-piperidine-1-oxyl) amino]-1,3,4-oxadiazoles labeled compounds

Chin. J. Org. Chem. ›› 1991, Vol. 11 ›› Issue (4): 404-407. Previous Articles Next Articles

Original Articles

2-芳基-5-[4'-(2,2,6,6,-四甲基哌啶-1-氧)氨基]-1,3,4-恶二唑自旋标记化合物的合成

张自义;施继成

兰州大学化学系;兰州大学应用有机化学国家重点实验室

发布日期:1991-08-25

Synthesis of 2-Aryl-5-[4'-(2,2,6,6-tetramethyl-piperidine-1-oxyl) amino]-1,3,4-oxadiazoles labeled compounds

ZHANG ZIYI;SHI JICHENG

Published:1991-08-25

Abstract

The title comps. [I; Ar = Ph, p-MeC6H4, o-MeOC6H4 (II), p- (III), o-, m-FC6H4, p-ClC6H4, p- (IV), o-BrC6H4, p-IC6H4, 2-phenyl-4-quinolinyl (V)] were prepared via cyclization of 0.01 mmol ArCONHNHCSQ in EtOH containing 40 mg Hg(OAc)2. In a preliminary screening, II-V were effective against Bacillus subtilis, Escherichia coli, Proteus vulgaris, and/or Staphylococcus aureus.

Key words: SYNTHESIS, PIPERIDINE P, ANTICARCINOGEN, SPIN LABEL, OXDIAZOLE P, STRUCTURAL ANALYSIS, LABELLED COMPOUNDS, ANTIBIOTIC PROPERTY, NITRO-OXY RADICAL

CLC Number:

O621

Cite this article

ZHANG ZIYI;SHI JICHENG. Synthesis of 2-Aryl-5-[4'-(2,2,6,6-tetramethyl-piperidine-1-oxyl) amino]-1,3,4-oxadiazoles labeled compounds[J]. Chin. J. Org. Chem., 1991, 11(4): 404-407.

Export EndNote|Reference Manager|ProCite|BibTeX|RefWorks

[1]	Penghui Li, Qingyang Xie, Fuxian Wan, Yuanhong Zhang, Lin Jiang. Synthesis and Fungicidal Activity of Novel Substituted Pyrimidine-5-carboxamides Bearing Cyclopropyl Moiety [J]. Chinese Journal of Organic Chemistry, 2024, 44(2): 650-656.
[2]	Fakai Zou, Nengzhong Wang, Hui Yao, Hui Wang, Mingguo Liu, Nianyu Huang. Regio- and Stereo-selective Synthesis of 1β-/3R-Aryl Thiosugar [J]. Chinese Journal of Organic Chemistry, 2024, 44(2): 593-604.
[3]	Luyao Li, Zhongwen He, Zhenguo Zhang, Zhenhua Jia, Teck-Peng Loh. Application of Triaryl Carbenium in Organic Synthesis [J]. Chinese Journal of Organic Chemistry, 2024, 44(2): 421-437.
[4]	Qinggang Mei, Qinghan Li. Recent Progress of Visible Light-Induced the Synthesis of C(3) (Hetero)arylthio Indole Compounds [J]. Chinese Journal of Organic Chemistry, 2024, 44(2): 398-408.
[5]	Weiqing Yang, Yanbing Ge, Yuanyuan Chen, Ping Liu, Haiyan Fu, Menglin Ma. Design and Synthesis of Fluorescent 1,8-Napthalimide Derivatives and Their Identification of Cysteine [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 180-194.
[6]	Shihang Yu, Jiawei Liu, Biyu An, Qinghua Bian, Min Wang, Jiangchun Zhong. Asymmetric Synthesis of the Contact Sex Pheromone of Neoclytus acuminatus acuminatus (Fabricius) [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 301-308.
[7]	Qianfan Zhao, Yongzheng Chen, Shiming Zhang. Application and Mechanism Study of Carbon-Based Metal-Free Catalysts in Organic Synthesis [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 137-147.
[8]	Shan Chen, Zhilin Chen, Qiong Hu, Yanshuang Meng, Yue Huang, Pingfang Tao, Liru Lu, Guobao Huang. Recognition of Bis-thiourea Tweezers to Neutral Molecules in Non-Polar Solvent [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 277-281.
[9]	Huakun Wang, Xiaolong Ren, Yining Xuan. Study of the Halide Salt Catalyzed [3＋2] Cycloaddition of α,β-Epoxy Carboxylate with Isocyanate [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 251-258.
[10]	Yukun Jin, Baoyi Ren, Fushun Liang. Visible Light-Mediated Selective C—F Bond Cleavage of Trifluoromethyl Groups and Its Application in Synthesizing gem-Difluoro-Containing Compounds [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 85-110.
[11]	Cuiyun Ma, Hailan Luo, Fuhua Zhang, Dan Guo, Shuxing Chen, Fei Wang. Green Biosynthesis, Photophysical Properties and Application of 3-Pyrrolyl BODIPY [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 216-223.
[12]	Bozhen Wang, Jie Zhang, Chunhui Nian, Mingming Jin, Miaomiao Kong, Wulan Li, Wenfei He, Jianzhang Wu. Synthesis and Antitumor Activity of 3,4-Dichlorophenyl Amides [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 232-241.
[13]	Yang Li, Jinding Yuan, Di Zhao. Deep Eutectic Solvent of 1,3-Dimethylurea/L-(+)-Tartaric Acid for the Green Synthesis of (E)-2-Styrylquinoline-3-carboxylic Acid Derivatives [J]. Chinese Journal of Organic Chemistry, 2023, 43(9): 3268-3276.
[14]	Dandan Sui, Nannan Cen, Ruoqu Gong, Yang Chen, Wenbo Chen. Supporting-Electrolyte-Free Electrochemical Synthesis of Trifluoromethylated Oxindoles in Continuous Flow [J]. Chinese Journal of Organic Chemistry, 2023, 43(9): 3239-3245.
[15]	Ruixia Cao, Yuping Jia. Synthesis and Biological Activity of Novel Pyrrolo[2,3-d]pyrimidine Derivatives Containing Coumarin [J]. Chinese Journal of Organic Chemistry, 2023, 43(9): 3304-3311.

2-芳基-5-[4'-(2,2,6,6,-四甲基哌啶-1-氧)氨基]-1,3,4-恶二唑自旋标记化合物的合成

Synthesis of 2-Aryl-5-[4'-(2,2,6,6-tetramethyl-piperidine-1-oxyl) amino]-1,3,4-oxadiazoles labeled compounds

PDF

Knowledge

Cited

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments