Chin. J. Org. Chem. ›› 2000, Vol. 20 ›› Issue (2): 251-254. Previous Articles     Next Articles

利用四氯乙烷胺化反应合成联氢化嘧啶衍生物的研究

郭生;李增春;徐鸿章;姚丽   

  1. 内蒙古民族师院化学系
  • 发布日期:2000-04-25

Synthesis of bis - (hexahydropyrimidines) through reaction of diaminoalkanes with sym - tetrachloroethane

Guo Sheng;Li Zengchun;Xu Hongzhang;Yao Li   

  • Published:2000-04-25

1,3 - diaminoalkanes react with sym - tetrachloroethane to give crystaline 2,2' -bis- (hexahydropyrimidine) derivatives 1~5, after treatment with aqua ammonia. Subsequently 1 was treated with different amounts of dichloromethane to give higher yields of 4a, 8b - trans - perhydro - 4, 5, 8a, 9a - tetraazafluorene (6) and 8b, 8c - cis - perhydro - 3a, 4a, 7a,I 8a -tetrazacyclopentanofluorene (7), The transormation mechanisms for cis - and trans - 6 and 7 are proposed.

Key words: CELLON (= TETRACHLOROETHANE), AMINATE, PYRIMIDINE P, ISOMER, DICHLOROMETHANE

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