Chin. J. Org. Chem. ›› 2001, Vol. 21 ›› Issue (12): 1161-1163. Previous Articles     Next Articles

对Niementowski反应的改进

刘志红;孙晓莉;张生勇   

  1. 第四军医大学化学教研室.
  • 发布日期:2001-12-25

An improved niementowski reaction

Liu Zhihong;Sun Xiaoli;Zhang Shengyong   

  1. Univ of No.4 Military Medicine, Teach Lab of Chem.
  • Published:2001-12-25

Five quinazolinone compounds, such as 6-X-4(3H)-quinazolinone(X=NO2, Cl, Br, I) and 1-furfuryl-6-sulfamide-7-chloro-4(1H)-quinazolinone, were synthesized by reaction of anthranilic acids with formamide in presence of phosphoryl chloride. The mechanism of this reaction was also studied.

Key words: SYNTHESIS, PHOSPHORUS OXYCHLORIDE, O-AMINOBENZOIC ACID P, REACTION MECHANISM, FORMAMIDE, QUINAZOLINONE P

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